Does Marijuana Treat Multiple Sclerosis? [Sativex (nabiximols), clinical trials, my experience]
Many people report that marijuana or marijuana extracts such as Sativex (nabiximols) are effective for multiple sclerosis symptoms. This video reviews some of the clinical trials, and I share experience with my own patients.
Information about medical cannabis from the national MS society: https://www.nationalmssociety.org/NationalMSSociety/media/MSNationalFiles/Professionals/Cannabis-and-Multiple-Sclerosis.pdf
Sativex and bladder symptoms: https://pubmed.ncbi.nlm.nih.gov/16186518/
randomized trial of multiple sclerosis central pain and sleep disturbances: https://pubmed.ncbi.nlm.nih.gov/16186518/
marijuana multiple sclerosis NARCOMS survey: https://pubmed.ncbi.nlm.nih.gov/29185555/
Sativex Product Monograph: https://pdf.hres.ca/dpd_pm/00016162.PDF
Advances in the Management of Multiple Sclerosis Spasticity: https://www.karger.com/Article/FullText/367616
A randomized, double-blind, placebo-controlled, parallel-group, enriched-design study of nabiximols* (Sativex(®): https://pubmed.ncbi.nlm.nih.gov/21362108/
Smoked cannabis for spasticity in multiple sclerosis: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3394820/
Systemic review of marijuana products in MS: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4011465/
Trial in the Lancet with MS bladder function as a secondary outcome: https://www.thelancet.com/action/showPdf?pii=S0140-6736%2803%2914738-1
CB2 receptor and the immune system: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3226756/ Cannabidiol protects oligodendrocyte progenitor cells from inflammation-induced apoptosis: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3388241/
Cannabidiol, Decrease the Activation of Encephalitogenic T Cells in EAE: https://pubmed.ncbi.nlm.nih.gov/26259697/
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Dr. Brandon Beaber is a board-certified neurologist with subspecialty training in multiple sclerosis and other immunological diseases of the nervous system. He is a partner in the Southern California Permanente Medical Group and practices in Downey, California (South Los Angeles). He has several publications on MS epidemiology and has participated in clinical trials for MS therapeutics. You can follow him on twitter @Brandon_Beaber where he regularly posts about MS news and research.
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Music: INNER GRACE – Copyright 2018 Wilton Vought Source: Really Really Free Music Link: https://youtu.be/wy9FL1-jup4 T
he video material by Dr. Brandon Beaber is general educational material on health conditions and is not intended to be used by viewers to diagnose or treat any individual’s medical condition. Specifically, this material is not a substitute for individualized diagnostic and treatment advice by a qualified medical/health practitioner, licensed in your jurisdiction, who has access to the relevant information available from diagnostic testing, medical interviews, and a physical examination. To the extent that Dr. Beaber endorses any lifestyle change, behavioral intervention, or supplements, the viewer should consult with a qualified healthcare professional to determine the safety and efficacy of the intervention in light of their individualized information.